Findings

What do systematic reviews say?

3 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 50%Moderate 2 · 50%High 0 · 0%

Oral misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · women undergoing first trimester abortion

Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).

2 findings from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 2.38 [1.46, 3.87]
3 studies · 1704 participants
Moderate
Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 3.68 [1.56, 8.71]
2 studies · 216 participants
Low

Sublingual misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · women undergoing first trimester abortion

Sublingual misoprostol showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 0.68 [0.22, 2.11]
2 studies · 3229 participants
Moderate

Sublingual misoprostol vs vaginal misoprostol

Failure to achieve complete abortion · first trimester abortion

Sublingual misoprostol alone showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol alone (low certainty).

1 finding from 1 review

Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
RR 0.69 [0.37, 1.28]
5 studies · 2705 participants
Low