Medical abortion administered by nurses may leads to higher failure to achieve complete abortion compared with by doctors (low certainty).
Medical abortion self‐administered at home showed no clear difference in failure to achieve complete abortion compared with administered (low certainty).
Mifepristone (600 mg) plus prostaglandin showed no clear difference in failure to achieve complete abortion compared with mifepristone (200 mg) plus prostaglandin (moderate certainty).
Oral misoprostol probably leads to higher failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).
Sublingual misoprostol showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol (moderate certainty).
It is very uncertain whether mifepristone alone changes failure to achieve complete abortion compared with mifepristone/prostaglandin (very low certainty).
Prostaglandin alone may leads to higher failure to achieve complete abortion compared with combined regimen (low certainty).
Sublingual misoprostol alone showed no clear difference in failure to achieve complete abortion compared with vaginal misoprostol alone (low certainty).
Misoprostol 800 µg plus mifepristone 200 mg probably leads to lower failure to achieve complete abortion compared with misoprostol 400 µg plus mifepristone 200 mg (moderate certainty).