Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Headline outcomes only

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No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Prophylactic or very early CPAP vs supportive care

Failed Treatment · preterm infants

It is very uncertain whether prophylactic or very early CPAP changes failed treatment defined as recurrent apnoea, hypoxia, hypercarbia… compared with supportive care (very low certainty).

1 finding from 1 review

Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
RR 0.6 [0.49, 0.74]
4 studies · 765 participants
Very low

Prophylactic CPAP vs very early CPAP

Failed Treatment · preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Prophylactic CPAP vs mechanical ventilation

Failed treatment defined as the need for mechanical ventilation · preterm infants

Prophylactic CPAP probably leads to lower failed treatment defined as the need for mechanical ventilation compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
RR 0.49 [0.45, 0.54]
2 studies · 1042 participants
Moderate