Findings

What do systematic reviews say?

13 questions · 13 findings · 2 reviews · Cystic Fibrosis and Genetic Disorders

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No studies found 3 · 23.1%GRADE not reported 0 · 0%Very low 5 · 38.5%Low 5 · 38.5%Moderate 0 · 0%High 0 · 0%

Hypertonic saline 7% vs hypertonic saline

FEV1 · children with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypertonic saline 7% vs hypertonic saline

FEV1 % predicted: relative change from baseline · children with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Hypertonic saline 7% vs xylitol

FEV1 · adults with cystic fibrosis

The review found no eligible studies for this question.

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypertonic saline 7% vs xylitol

FEV1 % predicted: relative change from baseline · adults with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Very low

Hypertonic saline 3% to 7% vs Normal saline

FEV1 · adults and children with cystic fibrosis (stable lung disease)

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 134 participants
Low

Hypertonic saline 3% to 7% vs Normal saline

FEV1 · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

The review found no eligible studies for this question.

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Hypertonic saline 3% to 7% vs Normal saline

FEV1 % predicted: relative change from baseline · adults and children with cystic fibrosis (stable lung disease)

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 246 participants
Very low

Hypertonic saline 3% to 7% vs Normal saline

FEV1 % predicted: relative change from baseline · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 130 participants
Low

Hypertonic saline vs rhDNase with

FEV1 · adults and children with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 47 participants
Very low

Hypertonic saline vs rhDNase with

FEV1 % predicted: relative change from baseline · adults and children with cystic fibrosis

1 finding from 1 review

Nebulised hypertonic saline for cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Inhalation before vs during airway clearance techniques

FEV1 % predicted · adults and children with cystic fibrosis

1 finding from 1 review

Timing of hypertonic saline inhalation for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 63 participants
Low

Inhalation during vs after airway clearance techniques

FEV1 % predicted · adults and children with cystic fibrosis

1 finding from 1 review

Timing of hypertonic saline inhalation for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Inhalation before vs after airway clearance techniques

FEV1 % predicted · adults and children with cystic fibrosis

1 finding from 1 review

Timing of hypertonic saline inhalation for cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low