Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

nHFV vs nIPPV following failure of initial non‐invasive respiratory support

Endotracheal intubation To discharge · ventilated preterm infants with failure of initial non‐invasive respiratory support

It is very uncertain whether nHFV changes endotracheal intubation To discharge compared with nIPPV following failure of initial non‐invasive respiratory support (very low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 1.23 [0.51, 2.98]
1 study · 39 participants
Very low

nHFV vs NIPPV or NIV

Endotracheal intubation To discharge · preterm infants with respiratory distress for initial respiratory support

nHFV showed no clear difference in endotracheal intubation To discharge compared with nIPPV used (low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 1.33 [0.76, 2.34]
5 studies · 228 participants
Low

nHFV vs NCPAP

Endotracheal intubation To discharge · newborn (term* and preterm) infants with respiratory distress for initial respiratory support

nHFV may leads to lower endotracheal intubation To discharge compared with nCPAP used (low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 0.52 [0.33, 0.82]
5 studies · 571 participants
Low

nHFV vs HFNC

Endotracheal intubation or reintubation To discharge · preterm infants with respiratory distress for initial respiratory support

It is very uncertain whether nHFV changes endotracheal intubation or reintubation To discharge compared with HFNC (very low certainty).

1 finding from 1 review

Non‐invasive high‐frequency ventilation in newborn infants with respiratory distress 2024 · Cochrane Headline outcomes only
RR 2.94 [0.65, 13.27]
1 study · 37 participants
Very low