Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 1 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

ACP light-cure adhesive vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel demineralization (DIAGNOdent score) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)

A single triple-blinded RCT found the ACP-containing adhesive reduced enamel demineralization versus a conventional adhesive over 6 months (ungraded).

1 finding from 1 review

nCaF2 primer vs Control Transbond primer

White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)

A single small split-mouth RCT found the nCaF2-containing primer reduced demineralization (DIAGNOdent) but showed no significant clinical white spot lesion difference at debonding (ungraded).

1 finding from 1 review