Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 66.7%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Any antihypertensive drug vs no antihypertensive drugs/placebo

Eclampsia · women with mild to moderate hypertension during pregnancy

It is very uncertain whether any antihypertensive drug changes eclampsia compared with no antihypertensive drugs/placebo (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.52 [0.13, 2.06]
7 studies · 713 participants
Very low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Severe pre‐eclampsia · women with mild to moderate hypertension during pregnancy

It is very uncertain whether any antihypertensive drug changes severe pre‐eclampsia compared with no antihypertensive drugs/placebo (very low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.56 [0.15, 2.02]
3 studies · 416 participants
Very low

Any antihypertensive drug vs no antihypertensive drugs/placebo

Proteinuria/pre‐eclampsia · women with mild to moderate hypertension during pregnancy

Any antihypertensive drug showed no clear difference in proteinuria/pre‐eclampsia compared with no antihypertensive drugs/placebo (low certainty).

1 finding from 1 review

Antihypertensive drug therapy for mild to moderate hypertension during pregnancy 2018 · Cochrane Headline outcomes only
RR 0.92 [0.75, 1.14]
23 studies · 2851 participants
Low