Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Hysterectomy (simple or radical) with neoadjuvant chemotherapy vs Radiotherapy alone

Disease or progression‐free survival Median · women with locally advanced cervical cancer

Hysterectomy (simple or radical) with neoadjuvant chemotherapy showed no clear difference in disease‐ or progression‐free survival Median compared with radiotherapy alone (moderate certainty).

1 finding from 1 review

Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer 2022 · Cochrane Headline outcomes only
HR 0.75 [0.53, 1.05]
3 studies · 571 participants
Moderate

Intervention not reported

Disease progression · patients with early stage cervical cancer

The intervention probably leads to lower disease progression (moderate certainty).

1 finding from 1 review

Adjuvant platinum‐based chemotherapy for early stage cervical cancer 2016 · Cochrane Headline outcomes only
HR 0.47 [0.3, 0.74]
2 studies · 297 participants
Moderate

Intervention not reported

Disease progression · patients with early stage cervical cancer

The intervention showed no clear difference in disease progression (low certainty).

1 finding from 1 review

Adjuvant platinum‐based chemotherapy for early stage cervical cancer 2016 · Cochrane Headline outcomes only
HR 1.34 [0.24, 7.66]
1 study · 71 participants
Low