Cochrane · systematic review · CD005342

Adjuvant platinum‐based chemotherapy for early stage cervical cancer

Falcetta, FS, Medeiros, LRF, Edelweiss, MI, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library

Gynaecological, Neuro-oncology and Orphan Cancer3 versionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
4
current version
GRADE rated
4
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Show all 3 versions

Summary of findings

Population: patients with early stage cervical cancer
3 questions
OutcomeEffectEvidenceStatus / GRADE
Death from all causes
HR 0.56 [0.36, 0.87]2 studies · 297 participantsModerate
Disease progression
HR 0.47 [0.3, 0.74]2 studies · 297 participantsModerate
Grade 4 toxicity3
RR 6.26 [2.5, 15.67]3 studies · 321 participantsModerate

Summary of findings

Population: patients with early stage cervical cancer
1 question
OutcomeEffectEvidenceStatus / GRADE
Disease progression
HR 1.34 [0.24, 7.66]1 study · 71 participantsLow
Downgraded: imprecision