Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Breast Cancer

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

OFS vs no OFS

Disease-free survival · women with early breast cancer

OFS leads to lower disease‐free survival (DFS) Median compared with no OFS (high certainty).

1 finding from 1 review

Ovarian suppression for adjuvant treatment of hormone receptor‐positive early breast cancer 2020 · Cochrane Headline outcomes only
HR 0.83 [0.77, 0.9]
10 studies · 8899 participants
High

Capecitabine‐containing regimens vs non‐capecitabine‐containing regimens or no chemotherapy

Disease-free survival · patients with early breast cancer

Capecitabine‐containing regimens showed no clear difference in disease‐free survival (DFS)median compared with non‐capecitabine‐containing regimens or no chemotherapy (moderate certainty).

1 finding from 1 review

Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer 2021 · Cochrane Headline outcomes only
HR 0.93 [0.86, 1.01]
8 studies · 13547 participants
Moderate