What do systematic reviews say?

Moderate vs low protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

Very early treatment vs expectant management

Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty).

• Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants 2020 · Cochrane Headline outcomes only
  RR 0.54 [0.05, 5.71]
  1 study · 79 participants
  Low

Very early treatment vs expectant management

Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe language delay at 18 to… compared with expectant management (low certainty).

• Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants 2020 · Cochrane Headline outcomes only
  RR 0.54 [0.1, 2.78]
  1 study · 79 participants
  Low

Very early treatment vs expectant management

Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe cognitive delay at 18… compared with expectant management (low certainty).

• Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants 2020 · Cochrane Headline outcomes only
  RR 0.27 [0.03, 2.31]
  1 study · 79 participants
  Low

High vs moderate protein concentration of human milk fortifier

• Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported