Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

201 questions · 212 findings · 77 reviews

No studies found 49 · 23.1%GRADE not reported 23 · 10.8%Very low 66 · 31.1%Low 48 · 22.6%Moderate 25 · 11.8%High 1 · 0.5%

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: mean scores at end of treatment (secondary outcome) · people with depression after stroke
1 finding from 1 review

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke
1 finding from 1 review

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether pharmacological intervention and non‐invasive brain stimulation… changes depression: < 50% reduction in scale scores at end of treatment… compared with a pharmacological intervention and sham stimulation or usual care… (very low certainty).

1 finding from 1 review

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke

It is very uncertain whether non‐invasive brain stimulation changes depression: < 50% reduction in scale scores at end of treatment… compared with sham non‐invasive brain stimulation and/or usual care (very low certainty).

1 finding from 1 review

Intervention not reported

Anxiety and depression: total scores on hospital anxiety and depression scale (HADS) (8 months) · Carers of elderly persons
1 finding from 1 review

Intervention not reported

Prevalence of depression or depressive symptoms (short term: up to 3 months postpartum) Measured by various scales ‐ EPDS, HADS · Women of any age who had given birth within one month of the intervention being offered

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

SF‐36 social function. Domain of SF‐36 considered representative of quality of life: mental health domain largely covered by depression and anxiety above: scale of 0‐100. Higher score indicated improved social function. Mean duration of · people with chronic hip, knee or hip and knee osteoarthritis
1 finding from 1 review