Findings

What do systematic reviews say?

7 questions · 11 findings · 2 reviews · Stroke

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No studies found 0 · 0%GRADE not reported 5 · 45.5%Very low 6 · 54.5%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.7 [0.55, 0.88]
8 studies · 1025 participants
Very low
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antidepressants vs placebo

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes depression: meeting study criteria for depression at end treatment… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
RR 0.5 [0.37, 0.68]
9 studies · 734 participants
Very low

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Non‐invasive brain stimulation and pharmacological intervention (combination) vs a pharmacological intervention and sham stimulation or usual care (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke

1 finding from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: meeting study criteria for depression at end of · people with depression after stroke

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.67 [0.39, 1.14]
2 studies · 130 participants
Very low

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

2 findings from 1 review

Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.77 [0.62, 0.95]
6 studies · 521 participants
Very low
Pharmacological, non‐invasive brain stimulation and psychological interventions, and their combination, for treating… 2023 · Cochrane Headline outcomes only
RR 0.85 [0.59, 1.21]
3 studies · 201 participants
Very low

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
RR 0.68 [0.49, 0.94]
2 studies · 607 participants
Very low