Surgically induced or chronic acid gastroesophageal reflux (experimental) vs Non-reflux control animals
Dental erosion, alveolar bone destruction and oral/pharyngeal lesions · Rat models with surgically induced or chronic acid gastroesophageal reflux
In experimental rat models, induced gastroesophageal reflux caused dental erosion, alveolar bone destruction and oral lesions compared with controls, supporting biological plausibility; evidence is ungraded animal research.
1 finding from 1 review
- Laryngopharyngeal reflux, gastroesophageal reflux and dental disorders: A systematic review. 2020 All outcomesExperimental animal (rat) modelsTwo rat-model studies found significantly higher rates of dental erosion, alveolar bone destruction and osteomyelitis (Higo) and shorter molar crown heights with dentin exposure, inflammatory infiltration and fibrosis…2 studiesGRADE not reported