Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Down syndrome vs Individuals without Down syndrome (healthy controls: siblings, schoolchildren or others)

Mean DMFT (decayed, missing, filled permanent teeth) · Individuals of all ages

Individuals with Down syndrome had a lower mean DMFT in permanent teeth than controls (pooled SMD -0.18, 95% CI -0.35 to -0.02; 6 studies; I2=20%); certainty of evidence not graded.

1 finding from 1 review

Association between Dental Caries and Down Syndrome: A Systematic Review and Meta-Analysis. 2015 All outcomes
Individuals with and without Down syndrome from referral centres, national databases and schools across China, Portugal, Jordan, Nigeria, Brazil and India; cross-sectional studies
SMD -0.18 [-0.35, -0.02]
6 studies · 718 participants
GRADE not reported

Slum / urban-disadvantaged setting vs Non-slum urban / general-urban / national population

Caries experience (mean DMFT) · Adult residents of slums and non-slum urban settings of LMICs

Mean DMFT ranges from 0.26 to 16.6 across LMIC urban/slum populations; ungraded.

1 finding from 1 review

Systematic review of oral health in slums and non-slum urban settings of Low and Middle-Income Countries (LMICs):… 2024 All outcomes
Cross-sectional · Urban slums and non-slum/general-urban settings, LMICs
Mean DMFT (usually reported at population level) ranged from 0.26 to 16.6 across studies; the Missing component was typically highest and the Filled component lowest, reflecting limited access to dental care.
12 studies
GRADE not reported