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Evidence found and GRADE certainty

394 questions · 795 findings · 66 reviews · Dental caries

No studies found 5 · 0.6%GRADE not reported 753 · 94.7%Very low 31 · 3.9%Low 4 · 0.5%Moderate 2 · 0.3%High 0 · 0%

T allele of AMELX rs17878486 vs C allele of AMELX rs17878486

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between T allele vs C allele of AMELX rs17878486 and dental caries susceptibility (T vs C model: OR 2.87, 95% CI 0.35-23.23) in the Control group: Caries-free subgroup; certainty not graded.

8 findings from 1 review
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CT genotype of AMELX rs2106416 vs CC genotype of AMELX rs2106416

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between CT genotype vs CC genotype of AMELX rs2106416 and dental caries susceptibility (CT vs CC model: OR 1.20, 95% CI 0.65-2.22) in the Ethnicity: Caucasian subgroup; certainty not graded.

3 findings from 1 review

GG genotype of ENAM rs1264848 vs AA + AG genotype of ENAM rs1264848

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between GG genotype vs AA + AG genotype of ENAM rs1264848 and dental caries susceptibility (GG vs AA + AG model: OR 1.09, 95% CI 0.53-2.23) in the Ethnicity: Mixed subgroup; certainty not graded.

6 findings from 1 review
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TT genotype of AMELX rs2106416 vs CC + CT genotype of AMELX rs2106416

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC + CT genotype of AMELX rs2106416 and dental caries susceptibility (TT vs CC + CT model: OR 1.67, 95% CI 0.44-6.34) in the Ethnicity: Caucasian subgroup; certainty not graded.

3 findings from 1 review

AG + GG genotype (G-allele carriers) of ENAM rs1264848 vs AA genotype of ENAM rs1264848

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between AG + GG genotype (G-allele carriers) vs AA genotype of ENAM rs1264848 and dental caries susceptibility (AG + GG vs AA model: OR 1.69, 95% CI 0.78-3.68) in the Ethnicity: Mixed subgroup; certainty not graded.

6 findings from 1 review
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TT genotype of AMELX rs946252 vs CC + CT genotype of AMELX rs946252

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC + CT genotype of AMELX rs946252 and dental caries susceptibility (TT vs CC + CT model: OR 0.73, 95% CI 0.19-2.87) in the Control group: Caries-free subgroup; certainty not graded.

6 findings from 1 review
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T allele of AMELX rs6639060 vs C allele of AMELX rs6639060

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between T allele vs C allele of AMELX rs6639060 and dental caries susceptibility (T vs C model: OR 1.08, 95% CI 0.63-1.85) in the Ethnicity: Caucasian subgroup; certainty not graded.

3 findings from 1 review

TT genotype of AMELX rs2106416 vs CC genotype of AMELX rs2106416

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC genotype of AMELX rs2106416 and dental caries susceptibility (TT vs CC model: OR 1.83, 95% CI 0.47-7.06); certainty not graded.

3 findings from 1 review

TT genotype of ENAM rs3796703 vs CC + CT genotype of ENAM rs3796703

Dental caries susceptibility · Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)

No significant association between TT genotype vs CC + CT genotype of ENAM rs3796703 and dental caries susceptibility (TT vs CC + CT model: OR 2.90, 95% CI 0.92-9.12); certainty not graded.

3 findings from 1 review