Findings

What do systematic reviews say?

9 questions · 10 findings · 1 reviews · Headline outcomes only

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No studies found 3 · 30%GRADE not reported 0 · 0%Very low 4 · 40%Low 2 · 20%Moderate 1 · 10%High 0 · 0%

Injectional interferon alpha‐2B vs Normal saline

Degree of penile curvature · men with chronic (≥ 12 months) Peyronie's disease (single plaque)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 103 participants
Very low

Injectional nicardipine vs Normal saline

Degree of penile curvature · men with chronic Peyronie's disease (plaques without calcification)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Injectional betamethasone vs Normal saline

Degree of penile curvature · men with Peyronie's disease (not defined)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Injectional collagenase vs placebo

Degree of penile curvature · men with Peyronie's disease (diagnosis of disease: at least 12 months, penile curvature: at least 30 degrees)

2 findings from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 136 participants
Low
Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 612 participants
Moderate

Injectional verapamil vs saline (short‐term)

Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 14 participants
Very low

Injectional Botox vs placebo

Degree of penile curvature · men with Peyronie's disease (stable phase)

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Potassium paraaminobenzoate vs placebo

Degree of penile curvature · men with acute (maximum of 12 months) Peyronie's disease with no prior treatment and no evidence of calcified plaques (pain during…

The review found no eligible studies for this question.

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extracorporeal shockwave therapy vs sham

Degree of penile curvature · men with Peyronie's disease (palpable plaque or pain)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 166 participants
Low

Penile traction therapy vs no treatment (short‐term)

Degree of penile curvature · men with Peyronie's disease (diagnosis of disease: varying, penile curvature: at least 30 degrees)

1 finding from 1 review

Non‐surgical therapies for Peyronie's disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 89 participants
Very low