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What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 7 findings · 3 reviews · Effective Practice and Organisation of Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 5 · 71.4%Low 0 · 0%Moderate 1 · 14.3%High 1 · 14.3%

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes adverse events ‐ death in past 12 months (RR > 1 denotes higher risk… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Adverse events ‐ death · adults with common mental disorders

It is very uncertain whether primary‐level worker‐led collaborative care changes adverse events ‐ death compared with usual care (very low certainty).

1 finding from 1 review

Intervention not reported

Intrapartum and neonatal deaths · nurses, midwives, physicians

The intervention showed no clear difference in intrapartum and neonatal deaths (high certainty).

1 finding from 1 review

Intervention not reported

Patient outcome: death, disability or dependency at 90 days · health professionals providing care to patients with stroke

The intervention showed no clear difference in patient outcome: death, disability or dependency at 90 days (moderate certainty).

1 finding from 1 review

Lay health worker‐ vs specialist‐led care

Adverse events ‐ death from suicide during intervention (RR > 1 denotes greater risk)Â · people with severe mental disorders

It is very uncertain whether lay health worker‐ changes adverse events ‐ death from suicide during intervention (RR > 1… compared with specialist‐led care (very low certainty).

1 finding from 1 review