Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 2 reviews · Pregnancy and Childbirth

No studies found 1 · 20%GRADE not reported 0 · 0%Very low 2 · 40%Low 0 · 0%Moderate 2 · 40%High 0 · 0%

Betamethasone acetate plus phosphate vs betamethasone phosphate – fetal/neonatal outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

It is very uncertain whether betamethasone acetate plus phosphate changes any known death after randomisation (fetal, neonatal, child, child… compared with betamethasone phosphate – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Betamethasone 12‐hourly vs 24‐hourly dosing – fetal/neonatal outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

It is very uncertain whether betamethasone 12‐hourly changes any known death after randomisation (fetal, neonatal, child, child… compared with 24‐hourly dosing – fetal/neonatal outcomes (very low certainty).

1 finding from 1 review

Ambroxol vs corticosteroid (betamethasone)

Perinatal mortality frequency of deaths of newborns · women at risk of preterm birth

Ambroxol showed no clear difference in perinatal mortality frequency of deaths of newborns compared with corticosteroid (betamethasone) (moderate certainty).

1 finding from 1 review

Dexamethasone vs betamethasone – child outcomes

Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth

Dexamethasone showed no clear difference in any known death after randomisation (fetal, neonatal, child, child… compared with betamethasone – fetal/neonatal outcomes (moderate certainty).

1 finding from 1 review