Findings

What do systematic reviews say?

9 questions · 9 findings · 5 reviews · Kidney and Transplant

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No studies found 3 · 33.3%GRADE not reported 0 · 0%Very low 4 · 44.4%Low 1 · 11.1%Moderate 1 · 11.1%High 0 · 0%

Antibiotics vs no antibiotics

Death (any case) Time frame: 2 to 4 weeks · solid organ transplant recipients

It is very uncertain whether antibiotics changes death (any case) Time frame: 2 to 4 weeks compared with no antibiotics (very low certainty).

1 finding from 1 review

Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
RR 0.27 [0.02, 3.69]
2 studies · 87 participants
Very low

Antibiotics vs no antibiotics

Graft loss including death · solid organ transplant recipients

It is very uncertain whether antibiotics changes graft loss (including death with functioning graft) Time frame: 2… compared with no antibiotics (very low certainty).

1 finding from 1 review

Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
RR 2.89 [0.12, 67.96]
1 study · 53 participants
Very low

Systemic antibiotics alone vs systematic antibiotics plus antibiotic lock solution

Death · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs no treatment

Death (any cause) · patients with diarrhoea due to Shiga toxin‐producing E. coli

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for preventing diarrhoea‐associated haemolytic uraemic syndrome 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antibiotics vs placebo

Death at 6 months · adults with renal vasculitis for maintenance therapy

Antibiotics showed no clear difference in death at 6 months compared with placebo (low certainty).

1 finding from 1 review

Interventions for renal vasculitis in adults 2020 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.76]
1 study · 81 participants
Low

Systemic antibiotics plus antibiotic lock solutions plus tissue plasminogen activator vs systemic antibiotics plus antibiotic lock solutions plus heparin

Death · patients on maintenance HD with CRBSI

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Extended vs short duration antibiotics

Death (any case) Time frame: 2 to 4 weeks · solid organ transplant recipients

It is very uncertain whether extended changes death (any cause) Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
RR 0.2 [0.01, 3.98]
1 study · 97 participants
Very low

Extended vs short duration antibiotics

Graft loss including death · solid organ transplant recipients

It is very uncertain whether extended changes graft loss (including death with functioning graft) Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Perioperative antibiotics for preventing post‐surgical site infections in solid organ transplant recipients 2020 · Cochrane Headline outcomes only
RR 0.99 [0.49, 2]
2 studies · 302 participants
Very low

Intervention not reported

Death (6 months to 8 years) · adults with asymptomatic bacteriuria

The intervention showed no clear difference in death (6 months to 8 years) (moderate certainty).

1 finding from 1 review

Antibiotics for asymptomatic bacteriuria 2015 · Cochrane Headline outcomes only
RR 0.99 [0.7, 1.41]
6 studies · 761 participants
Moderate