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Evidence found and GRADE certainty

3 questions · 6 findings · 2 reviews · Orthodontics

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Resin infiltration vs Baseline before resin infiltration

Color change · Patients with post-orthodontic white spot lesions and permanent dentition

Eckstein (2015) reported a statistically significant color-change effect.

4 findings from 1 review
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Experimental orthodontic adhesive containing amorphous fluorinated calcium phosphate nanoparticles (n-AFCP) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel remineralization extent and color change · Human enamel specimens around orthodontic brackets (in vitro)

In vitro, an n-AFCP-containing orthodontic primer showed significant enamel remineralization and less color change versus control in a single study (ungraded).

1 finding from 1 review

Resin infiltration vs Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change

Color change of white spot lesion (color difference, T0 to T1) · Patients with post-orthodontic white spot lesions and permanent dentition

ICON resin infiltration significantly improved the color of post-orthodontic white spot lesions at 6 months (pooled Cohen's d/SMD 1.36, 95% CI 1.14 to 1.59; 4 studies, 458 teeth), although heterogeneity was very high (I2=98%) with a heavy outlier (Kannan); not GRADE-rated.

1 finding from 1 review