Resin infiltration vs Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change: Color change of white spot lesion (color difference, T0 to T1)
- Population
- Patients with post-orthodontic white spot lesions and permanent dentition
- Intervention
- Resin infiltration
- Comparison
- Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change
- Outcome
- Color change of white spot lesion (color difference, T0 to T1)
ICON resin infiltration significantly improved the color of post-orthodontic white spot lesions at 6 months (pooled Cohen's d/SMD 1.36, 95% CI 1.14 to 1.59; 4 studies, 458 teeth), although heterogeneity was very high (I2=98%) with a heavy outlier (Kannan); not GRADE-rated.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Resin infiltration (ICON, low-viscosity infiltrative resin; DMG) vs Pre-treatment baseline before infiltration (T0); pooled as a within-arm before/after change Color change of white spot lesion (color difference, T0 to T1) · Patients with post-orthodontic white spot lesions (permanent dentition, after removal of fixed multibracket… · 6 months, Post-orthodontic patients after fixed appliance removal; permanent dentition; in vivo clinical trials ICON resin infiltration significantly improved the color of post-orthodontic white spot lesions at 6 months (pooled Cohen's d/SMD 1.36, 95% CI 1.14 to 1.59; 4 studies, 458 teeth), although heterogeneity was very high (I2=98%) with a heavy outlier (Kannan); not GRADE-rated. Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the… (2022) All outcomes | SMD 1.36 [1.14, 1.59] | 4 studies · 458 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Changes in the Color and Brightness of White Spots Associated with Orthodontic Treatment 6 Months after the Application of Infiltrative… 2022 All outcomes | December 2021 to May 2022 | 4 | Critically Low / Critically Low |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Esthetic improvements of postorthodontic white-spot lesions treated with resin infiltration and microabrasion: A split-mouth, randomized… · 2019 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.