Stroke · individuals with sickle cell disease who are at risk of a primary stroke who have not had previous long‐term red cell transfusions
Long‐term red cell transfusion probably leads to lower clinical stroke compared with no transfusion (moderate certainty).
1 finding from 1 review
Stroke · individuals with sickle cell disease who are at risk of a primary stroke who have had long‐term red cell transfusions to prevent a stroke
1 finding from 1 review
Stroke · individuals with sickle cell disease who have had a stroke who have had long‐term red cell transfusions to prevent another stroke
It is very uncertain whether long‐term red cell transfusion changes clinical stroke compared with hydroxyurea and phlebotomy (very low certainty).
1 finding from 1 review
Stroke · individuals with sickle cell disease who are at risk of a primary stroke who have had long‐term red cell transfusions to prevent a stroke
It is very uncertain whether long‐term red cell transfusion changes clinical stroke compared with no transfusion (very low certainty).
1 finding from 1 review
Stroke · prevention of SCI in people with SCD and abnormal TCD velocities
Long‐term RBC transfusion may leads to lower clinical stroke compared with standard care (low certainty).
1 finding from 1 review
Stroke · SCD‐related SAEs and clinical stroke in people with SCD at risk of stroke and no previous long‐term RBC transfusions
Long‐term RBC transfusions probably leads to lower clinical stroke compared with standard care (moderate certainty).
1 finding from 1 review
Stroke · prevention of SCI in people with SCD and normalised TCD velocities
It is very uncertain whether transfusions continued changes clinical stroke compared with transfusions halted (very low certainty).
1 finding from 1 review
Stroke · prevention of SCI in people with SCD who have not had a stroke (primary prevention)
1 finding from 1 review
Stroke · prevention of SCI in people with SCD who had a stroke (secondary prevention)
It is very uncertain whether hydroxyurea changes clinical stroke compared with RBC transfusion (very low certainty).
1 finding from 1 review
Stroke · prevention of SCI in people with SCD and normal TCD velocities
Long‐term RBC transfusion showed no clear difference in clinical stroke compared with standard care (low certainty).
1 finding from 1 review