Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Skin

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No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 2 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Combination terbinafine plus azole vs terbinafine

Clinical cure · participants with confirmed toenail onychomycosis

It is very uncertain whether combination terbinafine plus azole changes clinical cure compared with terbinafine monotherapy (very low certainty).

1 finding from 1 review

Oral antifungal medication for toenail onychomycosis 2017 · Cochrane Headline outcomes only
RR 1.41 [1.01, 1.97]
1 study · 176 participants
Very low

Azoles vs moderate‐potent corticosteroid/azole combinations

Duration of treatment until clinical cure Not assessed · patients with tinea cruris and tinea corporis

1 finding from 1 review

Topical antifungal treatments for tinea cruris and tinea corporis 2014 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Azoles vs moderate‐potent corticosteroid/azole combinations

Clinical cure · patients with tinea cruris and tinea corporis

It is very uncertain whether azoles changes clinical cure (immediately at end of treatment) Resolution of… compared with moderate‐potent corticosteroid/azole combinations (very low certainty).

1 finding from 1 review

Topical antifungal treatments for tinea cruris and tinea corporis 2014 · Cochrane Headline outcomes only
RR 0.67 [0.53, 0.84]
4 studies · 353 participants
Very low