Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Kidney and Transplant

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Prednisone vs placebo or supportive treatment

Any continuing kidney disease at 3 months (study with high risk of bias excluded) · patients with IgAV

Prednisone showed no clear difference in children with any continuing kidney disease at 3 months compared with placebo or supportive treatment (moderate certainty).

1 finding from 1 review

Interventions for preventing and treating kidney disease in IgA vasculitis 2023 · Cochrane Headline outcomes only
RR 0.83 [0.46, 1.52]
4 studies · 655 participants
Moderate

Prednisone vs placebo or supportive treatment

Children with any continuing kidney disease at 6 months · patients with IgAV

Prednisone showed no clear difference in children with any continuing kidney disease at 6 months compared with placebo or supportive treatment (moderate certainty).

1 finding from 1 review

Interventions for preventing and treating kidney disease in IgA vasculitis 2023 · Cochrane Headline outcomes only
RR 0.51 [0.24, 1.11]
3 studies · 379 participants
Moderate

Prednisone vs placebo or supportive treatment

Any continuing kidney disease at 12 months (study with high risk of bias excluded) · patients with IgAV

Prednisone showed no clear difference in children with any continuing kidney disease at 12 months compared with placebo or supportive treatment (low certainty).

1 finding from 1 review

Interventions for preventing and treating kidney disease in IgA vasculitis 2023 · Cochrane Headline outcomes only
RR 1.06 [0.38, 2.91]
3 studies · 455 participants
Low