Findings

What do systematic reviews say?

9 questions · 11 findings · 2 reviews

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No studies found 1 · 9.1%GRADE not reported 0 · 0%Very low 5 · 45.5%Low 1 · 9.1%Moderate 4 · 36.4%High 0 · 0%

Nicotine replacement therapy vs placebo

Change in weight (kg) · People who have quit smoking

Nicotine replacement therapy for smoking cessation showed no clear difference in mean weight change (kg) at end of treatment compared with placebo (moderate certainty).

3 findings from 1 review

Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
MD 0.52
21 studies · 2784 participants
Moderate
Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
MD 0.08
11 studies · 1021 participants
Moderate
Interventions for preventing weight gain after smoking cessation 2021 · Cochrane Headline outcomes only
MD 0.37
17 studies · 1463 participants
Moderate

Summary of findings: ECM vs NECT plus cimetidine

Change in weight (kg) · adults with cystic fibrosis

It is very uncertain whether summary of findings: ECM changes change in weight (kg) compared with NECT plus cimetidine (very low certainty).

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
MD 0.4
1 study · 12 participants
Very low

Summary of findings: ECM vs ECMM

Change in weight (kg) · children with cystic fibrosis and proven pancreatic insufficiency

The review found no eligible studies for this question.

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: ECM vs a different ECM

Change in weight (kg) · adults and children with cystic fibrosis

Summary of findings: ECM (Creon®) showed no clear difference in change in weight (kg) compared with a different ECM (moderate certainty).

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
MD 0
1 study · 83 participants
Moderate

Summary of findings: ECM vs TPE

Change in weight (kg) · children with cystic fibrosis

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Summary of findings: ECM vs other enteric‐coated preparations

Change in weight (kg) · children with cystic fibrosis

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 56 participants
Very low

Summary of findings: low‐dose vs high‐dose PERT

Change in weight (kg) · adults and children with cystic fibrosis

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Summary of findings: liprotamase vs porcine PERT

Change in weight (kg) · children aged 7 years or over and adults with cystic fibrosis

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 128 participants
Low

Summary of findings: ECM vs ECT

Change in weight (kg) · adults and children with cystic fibrosis

It is very uncertain whether summary of findings: ECM changes change in weight (kg) compared with ECT (very low certainty).

1 finding from 1 review

Pancreatic enzyme replacement therapy for people with cystic fibrosis 2020 · Cochrane Headline outcomes only
MD 0.32
2 studies · 41 participants
Very low