Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Common Mental Disorders

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 50%Low 1 · 16.7%Moderate 1 · 16.7%High 1 · 16.7%

Valproate vs lithium

Change in symptom severity at 3 weeks (secondary efficacy outcome) · Adults (aged 18 and over) with acute mania
1 finding from 1 review

Valproate vs OLANZAPINE

Change in symptom severity at 3 weeks (secondary efficacy outcome) · Adults (aged 18 and over) with acute mania
1 finding from 1 review

Valproate vs placebo

Change in symptom severity at 3 weeks (secondary efficacy outcome) · Adults (aged 18 and over) with acute mania
1 finding from 1 review

Valproate vs placebo

Change in symptom severity at 3 weeks (secondary efficacy outcome) · Children and adolescents with acute mania
1 finding from 1 review

Valproate vs RISPERIDONE

Change in symptom severity at 5 ‐ 12 weeks (secondary efficacy outcome) · Children and adolescents with acute mania
1 finding from 1 review

Valproate vs lithium

Change in symptom severity of mania rating scale at 8 weeks (secondary efficacy outcome) · Children and adolescents with acute mania
1 finding from 1 review