Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Acute Respiratory Infections

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Change in severity of overall symptoms: short‐term (1 to 2 days) Subjective severity score · patients with common cold

Antihistamines probably leads to lower change in severity of overall symptoms: short‐term Subjective… compared with placebo (moderate certainty).

1 finding from 1 review

Antihistamines for the common cold 2015 · Cochrane Headline outcomes only
OR 0.74 [0.6, 0.92]
3 studies · 1490 participants
Moderate

Change in severity of overall symptoms: short‐term (1 to 2 days) Subjective severity score · patients with common cold

Sedating antihistamines leads to lower change in severity of overall symptoms: short‐term (1 to 2 days)… compared with placebo (high certainty).

1 finding from 1 review

Antihistamines for the common cold 2015 · Cochrane Headline outcomes only
OR 0.76 [0.61, 0.95]
2 studies · 1427 participants
High