Findings

What do systematic reviews say?

20 questions · 22 findings · 9 reviews · Airways

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 18.2%Low 2 · 9.1%Moderate 14 · 63.6%High 2 · 9.1%

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life · idiopathic pulmonary fibrosis

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 194 participants
Moderate

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life at long‐term · idiopathic pulmonary fibrosis

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Low

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life · interstitial lung disease

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 478 participants
Moderate

Pulmonary rehabilitation vs no pulmonary rehabilitation

Change in quality of life at long‐term · interstitial lung disease

1 finding from 1 review

Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 240 participants
Low

Long‐acting beta2‐agonist plus tiotropium vs tiotropium

Change in quality of life · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease

1 finding from 1 review

Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist alone for… 2015 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 6709 participants
Moderate

Long‐acting beta2‐agonist plus tiotropium vs long‐acting beta2‐agonist alone

Change in quality of life · addition to tiotropium versus either tiotropium or LABA alone for chronic obstructive pulmonary disease

1 finding from 1 review

Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist alone for… 2015 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 3378 participants
Moderate

Inhaled corticosteroids vs placebo

Change in quality of life: SGRQ Scale: 0 to 100 · patients with stable chronic obstructive pulmonary disease

1 finding from 1 review

Inhaled corticosteroids versus placebo for stable chronic obstructive pulmonary disease 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 2507 participants
Moderate

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Non‐invasive ventilation during exercise training for people with chronic obstructive pulmonary disease 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Moderate

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

Change in the health‐related quality of life · post‐exacerbation COPD

2 findings from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 219 participants
Very low
Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 164 participants
Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

Change in the health‐related quality of life · stable COPD

2 findings from 1 review

Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 259 participants
Very low
Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 200 participants
Very low

Beclometasone/LABA vs LABA

Change in quality of life: SGRQ Scale: 0 to 100 · participants with stable stage 3 COPD, smokers and ex‐smokers with a minimum pack‐year history of 20

1 finding from 1 review

Beclometasone for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 465 participants
Moderate

LABA/LAMA vs LABA plus inhaled corticosteroid (ICS)

Change in SGRQ total score · stable COPD

Long‐acting muscarinic antagonist (LAMA) plus long‐acting… showed no clear difference in quality of life as measured by SGRQ total score change from baseline… compared with LABA plus inhaled corticosteroid (ICS) (moderate certainty).

1 finding from 1 review

Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) versus LABA plus inhaled corticosteroid… 2023 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 14437 participants
Moderate

Benralizumab 100 mg vs placebo

Change in SGRQ total score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1433 participants
High

Diaphragmatic breathing vs no breathing exercises

Health‐related quality of life Change in total score of St George Respiratory Questionnaire · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Moderate

Mepolizumab 100 mg vs placebo

Change in SGRQ total score · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1285 participants
Moderate