Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 0 · 0%Moderate 1 · 33.3%High 1 · 33.3%

Summary of findings table ‐ Silicone earplugs vs no earplugs

Cerebral palsy · preterm or very low birth weight infants

It is very uncertain whether summary of findings table ‐ Silicone earplugs changes cerebral palsy at 18 to 22 months' corrected age compared with no earplugs (very low certainty).

1 finding from 1 review

Noise or sound management in the neonatal intensive care unit for preterm or very low birth weight infants 2024 · Cochrane Headline outcomes only
RR 3 [0.15, 61.74]
1 study · 12 participants
Very low

Intervention not reported

Cerebral palsy at 18 to 24 months' corrected age · preterm infants with low birth weight

The intervention showed no clear difference in cerebral palsy at 18 to 24 months' corrected age (high certainty).

1 finding from 1 review

Early erythropoiesis‐stimulating agents in preterm or low birth weight infants 2020 · Cochrane Headline outcomes only
RR 0.72 [0.46, 1.13]
6 studies · 1172 participants
High

Prophylactic CPAP vs mechanical ventilation

Neurodevelopmental impairment at 18 to 22 months · preterm infants

Prophylactic CPAP showed no clear difference in neurodevelopmental impairment defined as cerebral palsy,… compared with mechanical ventilation (moderate certainty).

1 finding from 1 review

Prophylactic or very early initiation of continuous positive airway pressure (CPAP) for preterm infants 2021 · Cochrane Headline outcomes only
RR 0.91 [0.62, 1.32]
1 study · 976 participants
Moderate