What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Bleaching vs No bleaching (untreated control)

Caries susceptibility, enamel demineralisation, erosion, or microhardness · Permanent teeth or extracted human teeth with artificial lesions

The laboratory studies did not find increased susceptibility to caries or enamel demineralisation, but no firm conclusions can be drawn because of high risk of bias.

1 finding from 1 review

Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. 2020 All outcomes
Varied or not stated · laboratory setting
no estimate extracted
5 studies
GRADE not reported

Tooth bleaching (carbamide or hydrogen peroxide; home and/or in-office) vs No bleaching (untreated or pH-cycling control)

Caries susceptibility, enamel demineralisation, erosion, or microhardness · Permanent teeth / enamel specimens (in vitro)

Low-quality in vitro evidence suggests that bleaching of permanent teeth does not increase susceptibility to caries, demineralisation or erosion (ungraded); the clinical question could not be answered because only in vitro studies were available.

1 finding from 1 review

Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. 2020 All outcomes
In vitro laboratory studies
Four studies at high risk of bias and one study at moderate risk reached the overall conclusion that neither home- nor in-office bleaching of permanent teeth was associated with an increased susceptibility to…
5 studies
GRADE not reported