Tooth bleaching (carbamide or hydrogen peroxide; home and/or in-office) vs No bleaching (untreated or pH-cycling control): Caries susceptibility, enamel demineralisation, erosion, or microhardness
- Population
- Permanent teeth / enamel specimens (in vitro)
- Intervention
- Tooth bleaching (carbamide or hydrogen peroxide; home and/or in-office)
- Comparison
- No bleaching (untreated or pH-cycling control)
- Outcome
- Caries susceptibility, enamel demineralisation, erosion, or microhardness
Low-quality in vitro evidence suggests that bleaching of permanent teeth does not increase susceptibility to caries, demineralisation or erosion (ungraded); the clinical question could not be answered because only in vitro studies were available.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Tooth bleaching (carbamide or hydrogen peroxide; home or in-office) vs No bleaching (untreated or pH-cycling control) Enamel demineralisation and susceptibility to caries or acid erosion (microhardness, mineral loss) · Permanent teeth / enamel specimens (in vitro) · In vitro laboratory studies Low-quality in vitro evidence suggests that bleaching of permanent teeth does not increase susceptibility to caries, demineralisation or erosion (ungraded); the clinical question could not be answered because only in vitro studies were available. Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. (2020) All outcomes | Four studies at high risk of bias and one study at moderate risk reached the overall conclusion that neither home- nor in-office bleaching of permanent teeth was associated with an increased susceptibility to… | 5 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. 2020 All outcomes | 2018-07-01 | 15 | Low / Critically Low |
Studies behind the findings
The primary studies the full-text reviews tie to this outcome. Reviews with headline outcomes only do not list them here.
- Effect of 10% carbamide peroxide bleaching on sound and artificial enamel carious lesions · 2009 · included by 1 of these review
- Susceptibility to carieslike lesions after dental bleaching with different techniques. · 2007 · included by 1 of these review
- The effect of bleaching on enamel susceptibility to acid erosion and demineralisation · 2005 · included by 1 of these review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.