Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Hypoxia‐inducible factor (HIF) stabilisers vs placebo

Cardiovascular mortality · people with CKD (including HD and PD)

It is very uncertain whether hypoxia‐inducible factor (HIF) stabilisers changes cardiovascular death Median compared with placebo (very low certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 3.68 [0.19, 70.21]
10 studies · 1114 participants
Very low

Hypoxia‐inducible factor (HIF) stabilisers vs erythropoiesis‐stimulating agent (ESA)

Cardiovascular mortality · people with CKD (including HD and PD)

Hypoxia‐inducible factor (HIF) stabilisers showed no clear difference in cardiovascular death Median compared with erythropoiesis‐stimulating agent (ESA) (low certainty).

1 finding from 1 review

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only
RR 1.05 [0.88, 1.26]
17 studies · 10340 participants
Low