Hypoxia‐inducible factor (HIF) stabilisers vs placebo: Cardiovascular mortality
It is very uncertain whether hypoxia‐inducible factor (HIF) stabilisers changes cardiovascular death Median compared with placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Hypoxia‐inducible factor (HIF) stabilisers vs placebo Cardiovascular death Median · people with CKD (including HD and PD) It is very uncertain whether hypoxia‐inducible factor (HIF) stabilisers changes cardiovascular death Median compared with placebo (very low certainty). Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease (2022) · Cochrane Headline outcomes only | RR 3.68 [0.19, 70.21] | 10 studies · 1114 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease 2022 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.