Findings

What do systematic reviews say?

6 questions · 6 findings · 2 reviews · Kidney and Transplant

No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 0 · 0%High 0 · 0%

Cardiovascular mortality · heart failure with chronic kidney disease

ACUTE: Serelaxin showed no clear difference in cardiovascular death compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.47 [0.21, 1.08]
2 studies · 1395 participants
Low

Cardiovascular mortality · heart failure with chronic kidney disease

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Cardiovascular mortality · preventing bone disease in kidney transplant recipients

It is very uncertain whether vitamin D changes cardiovascular death compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for preventing bone disease in kidney transplant recipients 2019 · Cochrane Headline outcomes only
RR 0.57 [0.04, 7.57]
3 studies · 232 participants
Very low

Cardiovascular mortality · preventing bone disease in kidney transplant recipients

It is very uncertain whether bisphosphonate changes cardiovascular death compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Interventions for preventing bone disease in kidney transplant recipients 2019 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.58]
3 studies · 150 participants
Very low

All cardiovascular death · heart failure with chronic kidney disease

CHRONIC: ACEi or ARB showed no clear difference in cardiovascular death ( compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.81 [0.64, 1.01]
2 studies · 1368 participants
Low

All cardiovascular death · heart failure with chronic kidney disease

CHRONIC: Beta‐blockers may leads to lower cardiovascular death ( compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for heart failure in people with chronic kidney disease 2020 · Cochrane Headline outcomes only
RR 0.53 [0.35, 0.81]
3 studies · 2287 participants
Low