Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Cranberry extract / juice and proanthocyanidin (flavonoid) fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)

Biofilm morphological changes · Streptococcus mutans (in vitro cultures and biofilms)

Cranberry extract alters S. mutans biofilm morphology/architecture (4 studies; ungraded).

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
in vitro (laboratory)
Cranberry treatment disrupted biofilm integrity with agglutination/cell degradation at higher concentrations (Singhal), reduced polymicrobial biomass 38% at 96 h (Philip 2019), produced defective accumulation and…
4 studies
GRADE not reported

Grape seed extract (GSE) and its proanthocyanidin fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)

Biofilm morphological changes · Streptococcus mutans (in vitro cultures and biofilms)

Grape seed extract alters S. mutans biofilm morphology (2 studies; ungraded).

1 finding from 1 review

Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomes
in vitro (laboratory)
GSE decreased microcolony number and biofilm thickness at 2000 ug/mL (Furiga) and significantly altered bacterial cell structure with 50 ug/2 mL GSE candy (Nowaczyk).
2 studies
GRADE not reported