Grape seed extract (GSE) and its proanthocyanidin fractions vs Untreated or vehicle control (some studies vs positive antimicrobial controls, e.g. chlorhexidine/fluoride)
Biofilm formation (reduction) · Streptococcus mutans (in vitro cultures and biofilms)
Grape seed extract reduces S. mutans biofilm formation in vitro (5 studies; ungraded).
1 finding from 1 review
- Effect of flavonoids from grape seed and cranberry extracts on the microbiological activity of Streptococcus mutans: a… 2024 All outcomesin vitro (laboratory)GSE reduced biofilm formation: 89% (polymeric PAC) vs 79% (dealcoholized wine) (Daglia), inhibition at 4 mg/mL (Zhao), decreased microcolonies with 2000 ug/mL GSE + fluorinol (Furiga), reduction within 30 min…5 studiesGRADE not reported