Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Gut

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Metronidazole vs vancomycin

Bacteriologic Cure · patients with Clostridium difficile‐associated diarrhoea in adults

It is very uncertain whether metronidazole changes bacteriologic cure compared with vancomycin (very low certainty).

1 finding from 1 review

Antibiotic treatment for Clostridium difficile‐associated diarrhoea in adults 2017 · Cochrane Headline outcomes only
RR 0.85 [0.62, 1.17]
2 studies · 163 participants
Very low

Metronidazole vs vancomycin

Cure (combined symptomatic and bacteriologic cure) ‐ mild disease · patients with Clostridium difficile‐associated diarrhoea in adults

It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ mild disease compared with vancomycin (very low certainty).

1 finding from 1 review

Antibiotic treatment for Clostridium difficile‐associated diarrhoea in adults 2017 · Cochrane Headline outcomes only
RR 0.88 [0.71, 1.09]
1 study · 90 participants
Very low

Metronidazole vs vancomycin

Cure (combined symptomatic and bacteriologic cure) ‐ severe disease · patients with Clostridium difficile‐associated diarrhoea in adults

It is very uncertain whether metronidazole changes cure (combined symptomatic and bacteriologic cure) ‐ severe disease compared with vancomycin (very low certainty).

1 finding from 1 review

Antibiotic treatment for Clostridium difficile‐associated diarrhoea in adults 2017 · Cochrane Headline outcomes only
RR 0.74 [0.52, 1.04]
1 study · 82 participants
Very low