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What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 6 findings · 3 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 0 · 0%Moderate 3 · 50%High 1 · 16.7%

Early systemic postnatal corticosteroids vs placebo or no treatment

BPD (36 weeks' PMA) · preventing bronchopulmonary dysplasia in preterm infants

Early systemic postnatal corticosteroids probably leads to lower BPD (36 weeks' PMA) compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Systemic corticosteroids vs placebo or control

Bronchopulmonary dysplasia/chronic lung disease · preterm infants with chronic lung disease

Systemic corticosteroids (dexamethasone or hydrocortisone) probably leads to lower BPD at 36 weeks' PMA compared with control (placebo or nothing) (moderate certainty).

1 finding from 1 review

Early systemic postnatal corticosteroids vs placebo or no treatment

Death or bronchopulmonary dysplasia at 36 weeks PMA · preventing bronchopulmonary dysplasia in preterm infants

Early systemic postnatal corticosteroids leads to lower mortality or BPD at 36 weeks' PMA compared with placebo or no treatment (high certainty).

1 finding from 1 review

Systemic corticosteroids vs placebo or control

Death or bronchopulmonary dysplasia at 36 weeks PMA · preterm infants with chronic lung disease

Systemic corticosteroids (dexamethasone or hydrocortisone) probably leads to lower mortality or BPD at 36 weeks' PMA compared with control (placebo or nothing) (moderate certainty).

1 finding from 1 review