Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Pain, Palliative and Supportive Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

At least 50% of maximum pain relief over 4 to 6 h · Adults with acute pain

The intervention probably leads to higher at least 50% of maximum pain relief over 4 to 6 h (moderate certainty).

1 finding from 1 review

Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults 2015 · Cochrane Headline outcomes only
RR 5.5 [3.5, 8.7]
4 studies · 334 participants
Moderate