Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

21 questions · 21 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 9 · 42.9%Moderate 12 · 57.1%High 0 · 0%

0.2% NaF mouthrinse + supervised toothbrushing vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 0.98, 95% CI 0.84 to 1.14; low certainty).

1 finding from 1 review

Sealant (any type) vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Sealant was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 1.98, 95% CI 1.61 to 2.44; moderate certainty).

1 finding from 1 review

1.23% APF gel vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 2.13, 95% CI 1.79 to 2.54; moderate certainty).

1 finding from 1 review

Fluoride varnish vs Resin infiltration + 5% NaF varnish

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish was probably less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.62, 95% CI 0.46 to 0.83; moderate certainty).

1 finding from 1 review

1.23% APF gel vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 1.08, 95% CI 0.82 to 1.41; low certainty).

1 finding from 1 review

Resin infiltration + 5% NaF varnish vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Resin infiltration + 5% NaF varnish was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 3.2, 95% CI 2.24 to 4.56; moderate certainty).

1 finding from 1 review

Fluoride varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish may not differ from Sealant for arrest or reversal of occlusal carious lesions (RR 0.99, 95% CI 0.86 to 1.15; low certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing was probably less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.58, 95% CI 0.43 to 0.79; moderate certainty).

1 finding from 1 review

1.23% APF gel vs Fluoride varnish

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel may not differ from 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 1.08, 95% CI 0.83 to 1.4; low certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs Fluoride varnish

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing may not differ from 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.99, 95% CI 0.84 to 1.15; low certainty).

1 finding from 1 review

1.23% APF gel vs Resin infiltration + 5% NaF varnish

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel may be less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.67, 95% CI 0.45 to 0.99; low certainty).

1 finding from 1 review

1.23% APF gel vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

1.23% APF gel may be less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.64, 95% CI 0.44 to 0.92; low certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs 1.23% APF gel

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing may not differ from 1.23% APF gel for arrest or reversal of occlusal carious lesions (RR 0.91, 95% CI 0.68 to 1.22; low certainty).

1 finding from 1 review

Resin infiltration + 5% NaF varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Resin infiltration + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.61, 95% CI 1.16 to 2.24; moderate certainty).

1 finding from 1 review

Fluoride varnish vs Sealants plus fluoride varnish (with or without restorations)

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish was probably less effective than Sealant + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.59, 95% CI 0.45 to 0.76; moderate certainty).

1 finding from 1 review

Sealant + 5% NaF varnish vs Sealant

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Sealant + 5% NaF varnish was probably more effective than Sealant for arrest or reversal of occlusal carious lesions (RR 1.69, 95% CI 1.26 to 2.27; moderate certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs Resin infiltration + 5% NaF varnish

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing was probably less effective than Resin infiltration + 5% NaF varnish for arrest or reversal of occlusal carious lesions (RR 0.61, 95% CI 0.43 to 0.85; moderate certainty).

1 finding from 1 review

Fluoride varnish vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

5% NaF varnish was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 1.97, 95% CI 1.63 to 2.4; moderate certainty).

1 finding from 1 review

0.2% NaF mouthrinse + supervised toothbrushing vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

0.2% NaF mouthrinse + supervised toothbrushing was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 1.94, 95% CI 1.54 to 2.46; moderate certainty).

1 finding from 1 review

Sealant + 5% NaF varnish vs no treatment

Arrest or reversal of noncavitated occlusal carious lesions · Children and adults with noncavitated carious lesions on occlusal surfaces (primary and permanent teeth)

Sealant + 5% NaF varnish was probably more effective than no treatment for arrest or reversal of occlusal carious lesions (RR 3.35, 95% CI 2.42 to 4.64; moderate certainty).

1 finding from 1 review