Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 2 reviews

No studies found 11 · 91.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 1 · 8.3%

COMPARISON 1. ARIPIPRAZOLE vs placebo

Requirement for anticholinergics number of participants requiring medication for extrapyramidal side effects · patients with an acute manic or mixed episode

Aripiprazole leads to higher requirement for anticholinergics number of participants requiring… compared with placebo (high certainty).

1 finding from 1 review