Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Anomalies (all recorded) · prenatal diagnosis

Second trimester amniocentesis showed no clear difference in anomalies (all recorded) compared with control (moderate certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.93 [0.62, 1.39]
1 study · 4507 participants
Moderate

Anomalies (all recorded) · prenatal diagnosis

Early leads to higher anomalies (all recorded) compared with second trimester amniocentesis (high certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.73 [1.26, 2.38]
1 study · 4334 participants
High