Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Alpha diversity (Shannon) · Children providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples

In children, caries-vs-health Shannon alpha diversity differed significantly (ungraded).

1 finding from 1 review

Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes. 2022 All outcomes
Oral cavity microbiome (saliva and supragingival plaque samples); pooled across 19 international studies · Children
In children, the Shannon alpha-diversity index differed significantly between caries and health (p < 0.001).
Studies not reported
GRADE not reported

Alpha diversity (Chao1, Observed, Shannon) · Adults providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples

In adults, caries-vs-health alpha diversity differed for the Shannon index but not Chao1/Observed (ungraded).

1 finding from 1 review

Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes. 2022 All outcomes
Oral cavity microbiome (saliva and supragingival plaque samples); pooled across 19 international studies · Adults
In adults, there was no significant caries-vs-health difference in Chao1 or Observed diversity, whereas the Shannon index differed significantly (p < 0.001).
Studies not reported
GRADE not reported