Dental caries (carious oral microbiome) vs Caries-free / healthy oral microbiome
Alpha diversity (Chao1, Observed, Shannon) · Adults providing oral (saliva/supragingival plaque) 16S rRNA microbiome samples
In adults, caries-vs-health alpha diversity differed for the Shannon index but not Chao1/Observed (ungraded).
1 finding from 1 review
- Meta-analysis of caries microbiome studies can improve upon disease prediction outcomes. 2022 All outcomesOral cavity microbiome (saliva and supragingival plaque samples); pooled across 19 international studies · AdultsIn adults, there was no significant caries-vs-health difference in Chao1 or Observed diversity, whereas the Shannon index differed significantly (p < 0.001).Studies not reportedGRADE not reported