Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 1 · 33.3%

Second trimester amniocentesis vs control

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Second trimester amniocentesis showed no clear difference in all known pregnancy loss (including termination of pregnancy) compared with control (moderate certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.41 [0.99, 2]
1 study · 4606 participants
Moderate

Transabdominal chorionic villus sampling vs second trimester amniocentesis

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Transabdominal chorionic villus sampling showed no clear difference in all known pregnancy loss (including termination of pregnancy) compared with second trimester amniocentesis (low certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 0.9 [0.66, 1.23]
1 study · 2234 participants
Low

Early vs second trimester amniocentesis

All known pregnancy loss (including termination of pregnancy) · prenatal diagnosis

Early leads to higher all known pregnancy loss (including termination of pregnancy) compared with second trimester amniocentesis (high certainty).

1 finding from 1 review

Amniocentesis and chorionic villus sampling for prenatal diagnosis 2017 · Cochrane Headline outcomes only
RR 1.29 [1.03, 1.61]
1 study · 4334 participants
High