Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Hepato-Biliary

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Direct‐acting antivirals vs control

All‐cause mortality maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals changes all‐cause mortality at maximum compared with control (very low certainty).

1 finding from 1 review

Direct‐acting antivirals for chronic hepatitis C 2017 · Cochrane Headline outcomes only
OR 3.72 [0.53, 26.18]
11 studies · 2996 participants
Very low

Direct‐acting antivirals withdrawn from the market vs control

All‐cause mortality maximum · adults with chronic hepatitis C

It is very uncertain whether direct‐acting antivirals withdrawn from the market changes all‐cause mortality at maximum compared with control (very low certainty).

1 finding from 1 review

Direct‐acting antivirals for chronic hepatitis C 2017 · Cochrane Headline outcomes only
OR 0.64 [0.23, 1.79]
5 studies · 3045 participants
Very low