Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Heart

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Any glucocorticoid vs placebo

Mortality within the longest · Children having heart surgery with cardiopulmonary bypass

Glucocorticoid showed no clear difference in all‐cause mortality at longest compared with placebo (moderate certainty).

1 finding from 1 review

Prophylactic corticosteroids for paediatric heart surgery with cardiopulmonary bypass 2020 · Cochrane Headline outcomes only
RR 0.83 [0.33, 2.07]
5 studies · 313 participants
Moderate

Prophylactic corticosteroids vs placebo or no corticosteroids

Mortality within the longest · adults diagnosed with coronary artery disease or cardiac valve disease, and candidates for cardiac surgery with cardiopulmonary bypass

Prophylactic corticosteroids showed no clear difference in all‐cause mortality (during the index hospital admission, or within… compared with placebo or no corticosteroids (low certainty).

1 finding from 1 review

Prophylactic corticosteroids for cardiopulmonary bypass in adult cardiac surgery 2024 · Cochrane Headline outcomes only
RR 0.9 [0.75, 1.07]
25 studies · 14940 participants
Low