Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews · Vascular

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No studies found 1 · 14.3%GRADE not reported 4 · 57.1%Very low 1 · 14.3%Low 1 · 14.3%Moderate 0 · 0%High 0 · 0%

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)

All‐cause mortality · people who underwent a lower limb revascularisation

The review found no eligible studies for this question.

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

All‐cause mortality · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in all‐cause mortality compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
RR 1.11 [0.7, 1.74]
1 study · 594 participants
Low

BM‐MNCs vs mPBSCs

All‐cause mortality during hospital stay · people with critical limb ischaemia

1 finding from 1 review

Autologous cells derived from different sources and administered using different regimens for 'no‐option' critical… 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 202 participants
GRADE not reported

High cell dose vs low cell dose

All‐cause mortality during hospital stay · people with critical limb ischaemia

1 finding from 1 review

Autologous cells derived from different sources and administered using different regimens for 'no‐option' critical… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 16 participants
GRADE not reported

IM injection vs IA injection

All‐cause mortality during hospital stay · people with critical limb ischaemia

1 finding from 1 review

Autologous cells derived from different sources and administered using different regimens for 'no‐option' critical… 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 95 participants
GRADE not reported

BM‐MNCs vs BM‐MSCs

All‐cause mortality during hospital stay · people with critical limb ischaemia

1 finding from 1 review

Autologous cells derived from different sources and administered using different regimens for 'no‐option' critical… 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
GRADE not reported

Intramuscular injection of bone marrow mononuclear cells (BMMNC) vs control

All‐cause mortality ( · people with CLI who were not suitable for revascularisation and showed no improvement in response to the best standard therapy

It is very uncertain whether intramuscular injection of bone marrow mononuclear cells (BMMNC) changes all‐cause mortality ( compared with control (very low certainty).

1 finding from 1 review

Local intramuscular transplantation of autologous bone marrow mononuclear cells for critical lower limb ischaemia 2022 · Cochrane Headline outcomes only
RR 1 [0.15, 6.63]
3 studies · 123 participants
Very low