Findings

What do systematic reviews say?

14 questions · 14 findings · 4 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 4 · 28.6%Very low 1 · 7.1%Low 5 · 35.7%Moderate 4 · 28.6%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Regular salmeterol vs placebo · All‐cause mortality ‐ adults and adolescents
  Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
  OR 1.33 [0.85, 2.08]
  10 studies · 29128 participants
  Moderate
Direct match · question page
- Regular salmeterol vs regular salbutamol · All‐cause mortality ‐ adults and adolescents
  Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
  OR 1.28 [0.79, 2.05]
  4 studies · 26463 participants
  Moderate
Direct match
- · All‐cause mortality
  Inhaled steroids with and without regular salmeterol for asthma: serious adverse events 2018 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 8453 participants
  Moderate
Direct match
- · All‐cause mortality
  Inhaled steroids with and without regular salmeterol for asthma: serious adverse events 2018 · Cochrane Headline outcomes only
  OR 0.8 [0.36, 1.78]
  41 studies · 27951 participants
  Moderate
Related · question page
- Adults: formoterol/ICS vs salmeterol/ICS · All‐cause mortality ‐ formoterol/mometasone vs salmeterol/fluticasone
  Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
  OR 4.46 [0.23, 85.4]
  2 studies · 1126 participants
  Low

Regular salmeterol vs salbutamol

All‐cause mortality ‐ children · patients with chronic asthma

Regular salmeterol showed no clear difference in all‐cause mortality ‐ children compared with regular salbutamol (low certainty).

1 finding from 1 review

Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
OR 0.04 [0, 2.97]
3 studies · 1152 participants
Low

Regular salmeterol vs salbutamol

All‐cause mortality ‐ adults and adolescents · patients with chronic asthma

Regular salmeterol showed no clear difference in all‐cause mortality ‐ adults and adolescents compared with regular salbutamol (moderate certainty).

1 finding from 1 review

Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
OR 1.28 [0.79, 2.05]
4 studies · 26463 participants
Moderate

Regular salmeterol vs placebo

All‐cause mortality ‐ children · patients with chronic asthma

1 finding from 1 review

Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1126 participants
GRADE not reported

Regular salmeterol vs placebo

All‐cause mortality ‐ adults and adolescents · patients with chronic asthma

Regular salmeterol showed no clear difference in all‐cause mortality ‐ adults and adolescents compared with placebo (moderate certainty).

1 finding from 1 review

Regular treatment with salmeterol for chronic asthma: serious adverse events 2008 · Cochrane Headline outcomes only
OR 1.33 [0.85, 2.08]
10 studies · 29128 participants
Moderate

Regular formoterol vs regular salmeterol

All‐cause mortality in adults · people with asthma

1 finding from 1 review

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events 2012 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1116 participants
Low

Regular formoterol vs regular salmeterol

All‐cause mortality in children · people with asthma

1 finding from 1 review

Regular treatment with formoterol versus regular treatment with salmeterol for chronic asthma: serious adverse events 2012 · Cochrane Headline outcomes only
no estimate extracted
1 study · 156 participants
Very low

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality formoterol/budesonide vs salmeterol/budesonide · adults, chronic asthma: all‐cause mortality

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 229 participants
GRADE not reported

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol and budesonide vs salmeterol and fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/budesonide vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 1.03 [0.06, 16.44]
7 studies · 5935 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol/mometasone vs salmeterol/fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/mometasone vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 4.46 [0.23, 85.4]
2 studies · 1126 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

All‐cause mortality ‐ formoterol/fluticasone vs salmeterol/fluticasone · adults, chronic asthma: all‐cause mortality

Adults: formoterol/ICS showed no clear difference in all‐cause mortality ‐ formoterol/fluticasone vs salmeterol/fluticasone compared with salmeterol/ICS (low certainty).

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
OR 7.39 [0.15, 372.38]
2 studies · 270 participants
Low

Adults: formoterol/ICS vs salmeterol/ICS

Mortality (all‐cause) ‐ formoterol versus salbutamol ( · adults, chronic asthma: all‐cause mortality

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 1257 participants
GRADE not reported

Children: formoterol/fluticasone vs regular salmeterol and fluticasone

All‐cause mortality · children with chronic asthma

1 finding from 1 review

Regular treatment with formoterol and an inhaled corticosteroid versus regular treatment with salmeterol and an… 2021 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 548 participants
GRADE not reported

Intervention not reported

All‐cause mortality · adults and children with chronic asthma

The intervention showed no clear difference in all‐cause mortality (moderate certainty).

1 finding from 1 review

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events 2018 · Cochrane Headline outcomes only
OR 0.8 [0.36, 1.78]
41 studies · 27951 participants
Moderate

Intervention not reported

All‐cause mortality · adults and children with chronic asthma

1 finding from 1 review

Inhaled steroids with and without regular salmeterol for asthma: serious adverse events 2018 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 8453 participants
Moderate